Brock Purdy takes a 5-0 record against the Seahawks into Sunday's game, while counterpart Geno Smith looks for his first win ...

The Seahawks are coming off a bye, having lost five of their past six games. The 49ers have won back-to-back games for the ...

San Francisco 49ers running back Christian McCaffrey made his 2024 season debut on Sunday against the Tampa Bay Buccaneers, ...

Tampa Bay Buccaneers Tackle Luke Goedeke was mic'd up for Week 10's Salute to Service game against the San Francisco 49ers. Hear from Luke in this week's edition of Mic'd Up.

Star pass-catcher George Kittle and the San Francisco 49ers face the Seattle Seahawks on Sunday at 4:05 p.m. ET, at Levi’s ...

The San Francisco 49ers have another important division game on Sunday, but they may have to play without two of their biggest stars.

Analyzing NFL Week 11 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

We went 4-1 straight up on our top five picks, but 1-4 against the spread. The Baltimore Ravens defeated the Cincinnati ...

The San Francisco 49ers have a new weekly problem to solve now that running back Christian McCaffrey has returned from ...

San Francisco treaded water without Christian McCaffrey. Now that the NFL's reigning Offensive Player of the Year is back, it ...