Barring a sudden physical setback, San Francisco running back Christian McCaffrey will make his season debut on Sunday ...

To help us preview the Indianapolis Colts’ Week 10 matchup with Buffalo, Bills Wire answered five key questions to provide ...

Joe Flacco will make his second straight start for Indianapolis when the Buffalo Bills come to town Sunday, and they're ...

The Buffalo Bills have won five straight games after losing two big games to the division-leading Houston Texans and ...

The Colts (4-5) open the week trailing Denver by a game for the final playoff spot in the AFC, but Cincinnati has caught Indianapolis, and suddenly it feels like the race is four teams — Colts, ...

The Indianapolis Colts have the second-worst run defense in the NFL right now, allowing 149.8 yards on the ground per game. Running back James Cook and company should be ready to capitalize on that.

NFL Week 10 is here, and it’s time to lock in some best bets and props before the games kick off. Picking matchups against ...

Indianapolis Colts quarterback Joe Flacco took a long, honest look at last week’s game tape and came to one conclusion. He ...

For the second week in a row, the Bills will be playing a desperate team. They survived at home against division rival Miami, ...

What to look for from the top Bills and Colts players and how to watch the game as they face off on Sunday, week 10.

The Bills have won four straight games while the Colts have lost two in a row, but it may be surprising to learn that Buffalo ...