The U.S. has been targeting Houthi facilities in Yemen and has long carried out military activities in the country.
Director-General of the World Health Organization, Tedros Adhanom Ghebreyesus, says he was close to the departure lounge when it was hit.
Israel is signaling a wider campaign against Houthi militants in Yemen, a mountainous and impoverished country more than 1,000 miles from Israeli territory.
An advanced U.S. military anti-missile system was used in Israel to try to intercept a projectile for the first time since President Joe Biden placed the system in Israel in October, a source familiar with the matter told Reuters on Friday.
An official says the Yemeni group will not stop until the war in Gaza ends, as Israel's PM says it is "just getting started".
The head of the World Health Organization said on Friday he was not sure he was going to survive an air strike on Yemen's main airport carried out by Israel a day earlier during a series of attacks on the Iran-aligned Houthi movement.
Flights were scheduled to resume again on Friday at Sanaa international airport, officials said, a day after the airport was hit by Israeli strikes.
World Health Organization chief Tedros Adhanom Ghebreyesus was about to board a plane at the Sanaa International Airport when it came under attack. A crew member on the plane was injured, he said.
Several people were killed on Thursday and dozens wounded in Israeli airstrikes on the main civilian airport in the Houthi rebel-held capital of Yemen.
Even as battles with its enemies on its borders appear to be winding down, Israel is being challenged by intensifying attacks by the Houthi militia in Yemen, 1,000 miles away.