Advanced systemic mastocytosis is a progressive condition characterized by the accumulation of mast cells in the body’s organs. There’s no cure for advanced systemic mastocytosis, but many of the ...

Advanced systemic mastocytosis is a progressive disorder that causes the atypical buildup of mast cells in different organs in the body. Treatment aims to slow the progression of the condition and ...

Advanced systemic mastocytosis (advSM) is a rare and serious form of systemic mastocytosis, a blood disorder that involves the overproduction of mast cells. Mast cells are a type of white blood cell ...

A diagnosis of advanced systemic mastocytosis (advSM), a rare blood disorder in which too many mast cells accumulate in various parts of the body, can cause a range of strong emotions. AdvSM sometimes ...

Patients with indolent mastocytosis may express concern about anaphylaxis or milder reactions to various substances, but Dr. Aaron T. Gerds, of Cleveland Clinic, reminds them that "you can't go into a ...

Systemic mastocytosis is a myeloid neoplasm divided into six subcategories by the recent classification by WHO. It involves the accumulation of abnormal mast cells (MCs) in the skin, liver, spleen, ...

Patients with indolent mastocytosis may express concern about anaphylaxis or milder reactions to various substances, but Dr. Aaron T. Gerds, of Cleveland Clinic, reminds them that "you can't go into a ...

Avapritinib (Ayvakit, Blueprint Medicines), a novel agent that targets a specific mutation found in 90% of patients with systemic mastocytosis, reduces skin lesions and mast cell burden, according to ...

Systemic mastocytosis and mast cell activation syndrome both negatively impact health-related quality of life (HRQOL), with mast cell activation syndrome patients reporting more significant impacts on ...

Please provide your email address to receive an email when new articles are posted on . "Ayvakit is the first and only medicine approved by the FDA to treat indolent systemic mastocytosis, marking a ...

The National Institute for Health and Care Excellence has recommended avapritinib (Ayvakyt) as a treatment option for adults with advanced systemic mastocytosis. Mastocytosis is a rare group of ...