UCI’s $12M CIRM award for hNSC-01 marks a pivotal shift to clinical-stage development. See how this state-funded "bridge" is ...

An experimental gene therapy seems to slow the progression of Huntington’s disease by about 75 per cent, and researchers are ...

For the first time, scientists have successfully treated someone suffering from Huntington's disease, a fatal genetic illness ...

In a small trial, a gene therapy injected into the brain slowed the disease by 75 percent over three years. Huntington’s disease is extremely cruel. Symptoms start with random, uncontrollable twitches ...

AUSTIN (KXAN) — An exceptionally rare and fatal genetic disease may finally have a solution. Huntington’s Disease affects one in ten to twenty thousand Americans. The disease is a mixture of dementia ...

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding ...

Gene therapy is becoming a powerful way to treat challenging diseases that don’t respond to traditional treatments, and researchers now report the first success in modifying genes to slow Huntington’s ...

BUFFALO, N.Y. — A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease?

Using RNA to interfere with a gene’s expression of disease-causing proteins is a validated therapeutic approach, but so far, the products in this drug class only address liver proteins. Reducing ...

Huntington’s disease is horrible. It is also odd. Illnesses caused by inherited aberrant genes are mostly what geneticists call “recessive”, meaning someone must receive defective versions of the gene ...

Study uncovers how gradual CAG repeat expansion in neurons drives the onset of Huntington’s disease, offering new insights for potential therapeutic interventions. Study: Long somatic DNA-repeat ...