Medically reviewed by Steffini Stalos, DO Key Takeaways CD4 T helper cells help the body fight infections by signaling other cells to attack germs. Without enough CD4 T cells, the body can't fight ...

Knowable Magazine reports on breakthroughs in HIV treatment; engineered antibodies show promise for long-term control, hinting at a functional cure.

A natural vitamin A transporter, RBP4, can awaken latent HIV through NF-κB signalling, offering a new angle for cure ...

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a ...

Rare case shows a man living virus free for years after stopping treatment, raising new questions about how the immune system ...

The global challenge posed by HIV-1 infection continues to drive research into its underlying mechanisms and the host immune response. Central to this pursuit is the role of T cells, particularly CD4 ...

For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating-and possibly even curing-the disease a seemingly insurmountable obstacle to achieve. But ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...

May 2, 2012 — Gene transfer using a retroviral vector that directs a patient's T cells to recognize HIV appears to be safe and persistent, according to a study published May 2 in Science Translational ...

Led by a team of African researchers, first doses of the novel T cell-inducing GRAdHIVNE1 vaccine candidate have been given. HARARE, ZIMBABWE, ROME, ITALY, NEW YORK, NY, AND CAMBRIDGE, MA / ACCESS ...

A few decades ago, the idea of an HIV cure sounded unrealistic. Today, doctors describe a carefully documented case where the ...